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Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation

Elevated pro-inflammatory cytokines exist in both blood and brain of people with schizophrenia but how this affects molecular indices of the blood–brain barrier (BBB) is unclear. Eight mRNAs relating to BBB function, a microglia and three immune cell markers were measured by qPCR in the prefrontal c...

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Publicado en:Mol Psychiatry
Main Authors: Cai, Helen Q., Catts, Vibeke S., Webster, Maree J., Galletly, Cherrie, Liu, Dennis, O’Donnell, Maryanne, Weickert, Thomas W, Weickert, Cynthia Shannon
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156343/
https://ncbi.nlm.nih.gov/pubmed/30214039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0235-x
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