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Overexpression of Bcl-2 in the intestinal epithelium prevents sepsis-induced gut barrier function via altering tight junction protein expression
Sepsis induces both intestinal hyperpermeability and epithelial apoptosis. While each has been implicated in mediating sepsis mortality, the relationship between these two processes is unclear. We hypothesized that preventing intestinal apoptosis would prevent gut barrier dysfunction. To test this h...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Shock |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7156322/ https://ncbi.nlm.nih.gov/pubmed/31626040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001463 |
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