Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors

miRNAs regulate post-transcriptional gene expression in metazoans, and thus are involved in many fundamental cellular biological processes. Extracellular miRNAs are also found in most human biofluids including plasma. These circulating miRNAs constitute a long distance inter cellular communication s...

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Vydáno v:PLoS One
Hlavní autoři: Castro-Magdonel, Blanca Elena, Orjuela, Manuela, Alvarez-Suarez, Diana E., Camacho, Javier, Cabrera-Muñoz, Lourdes, Sadowinski-Pine, Stanislaw, Medina-Sanson, Aurora, Lara-Molina, Citlali, García-Vega, Daphne, Vázquez, Yolanda, Durán-Figueroa, Noé, Orozco-Romero, María de Jesús, Hernández-Ángeles, Adriana, Ponce-Castañeda, M. Verónica
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156076/
https://ncbi.nlm.nih.gov/pubmed/32287312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231394
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