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Cascade trifluoromethylthiolation and cyclization of N-[(3-aryl)propioloyl]indoles
A cascade oxidative trifluoromethylthiolation and cyclization of N-[(3-aryl)propioloyl]indoles with AgSCF(3) is described. This protocol allows for the synthesis of novel bis(trifluoromethylthiolated) or trifluoromethylthiolated pyrrolo[1,2-a]indol-3-ones in moderate to good yields. Mechanistic inve...
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| Izdano u: | Beilstein J Org Chem |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Beilstein-Institut
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155893/ https://ncbi.nlm.nih.gov/pubmed/32318122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.62 |
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