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Cascade trifluoromethylthiolation and cyclization of N-[(3-aryl)propioloyl]indoles

A cascade oxidative trifluoromethylthiolation and cyclization of N-[(3-aryl)propioloyl]indoles with AgSCF(3) is described. This protocol allows for the synthesis of novel bis(trifluoromethylthiolated) or trifluoromethylthiolated pyrrolo[1,2-a]indol-3-ones in moderate to good yields. Mechanistic inve...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Bi, Ming-Xi, Liu, Shuai, Huang, Yangen, Xu, Xiu-Hua, Qing, Feng-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155893/
https://ncbi.nlm.nih.gov/pubmed/32318122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.62
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