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Targeting tumor neoangiogenesis via targeted adenoviral vector to achieve effective cancer gene therapy for disseminated neoplastic disease

The application of cancer gene therapy has heretofore been restricted to local, or locoregional, neoplastic disease contexts. This is owing to the lack of gene transfer vectors which embody the requisite target cell selectivity in vivo required for metastatic disease applications. To this end, we ha...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Lee, Myungeun, Lu, Zhi Hong, Li, Jie, Kashentseva, Elena A., Dmitriev, Igor P., Mendonca, Samir A., Curiel, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155772/
https://ncbi.nlm.nih.gov/pubmed/31907220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0768
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