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Targeting tumor neoangiogenesis via targeted adenoviral vector to achieve effective cancer gene therapy for disseminated neoplastic disease

The application of cancer gene therapy has heretofore been restricted to local, or locoregional, neoplastic disease contexts. This is owing to the lack of gene transfer vectors which embody the requisite target cell selectivity in vivo required for metastatic disease applications. To this end, we ha...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Lee, Myungeun, Lu, Zhi Hong, Li, Jie, Kashentseva, Elena A., Dmitriev, Igor P., Mendonca, Samir A., Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155772/
https://ncbi.nlm.nih.gov/pubmed/31907220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0768
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