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Chronic morphine regulates TRPM8 channels via MOR-PKCβ signaling
Postoperative shivering and cold hypersensitivity are major side effects of acute and chronic opioid treatments respectively. TRPM8 is a cold and menthol-sensitive channel found in a subset of dorsal root ganglion (DRG) nociceptors. Deletion or inhibition of the TRPM8 channel was found to prevent th...
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| Publicado no: | Mol Brain |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155267/ https://ncbi.nlm.nih.gov/pubmed/32290846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00599-0 |
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