Loading...
Metal Exchange in the Interprotein Zn(II)‐Binding Site of the Rad50 Hook Domain: Structural Insights into Cd(II)‐Induced DNA‐Repair Inhibition
Cd(II) is a major genotoxic agent that readily displaces Zn(II) in a multitude of zinc proteins, abrogates redox homeostasis, and deregulates cellular metalloproteome. To date, this displacement has been described mostly for cysteine(Cys)‐rich intraprotein binding sites in certain zinc finger domain...
Na minha lista:
| Udgivet i: | Chemistry |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155053/ https://ncbi.nlm.nih.gov/pubmed/31846102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201904942 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|