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Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella‐containing vacuole

Legionella pneumophila requires the Dot/Icm translocation system to replicate in a vacuolar compartment within host cells. Strains lacking the translocated substrate SdhA form a permeable vacuole during residence in the host cell, exposing bacteria to the host cytoplasm. In primary macrophages, muta...

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Publicado en:Cell Microbiol
Autores principales: Anand, Ila S., Choi, Wonyoung, Isberg, Ralph R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154685/
https://ncbi.nlm.nih.gov/pubmed/32096265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13151
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