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Insights into the Role of Ketoreductases in the Biosynthesis of Partially Reduced Bacterial Aromatic Polyketides*

Partially reduced aromatic polyketides are bioactive secondary metabolites or intermediates in the biosynthesis of deoxygenated aromatics. For the antibiotic GTRI‐02 (mensalone) in different Streptomyces spp., biosynthesis involving the reduction of a fully aromatized acetyltrihydroxynaphthalene by...

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Dettagli Bibliografici
Pubblicato in:Chembiochem
Autori principali: Husain, Syed Masood, Präg, Andreas, Linnenbrink, Anton, Bechthold, Andreas, Müller, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154522/
https://ncbi.nlm.nih.gov/pubmed/31507033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900357
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