Clinical pharmacokinetics and drug exposure-toxicity correlation study of docetaxel based chemotherapy in Chinese head and neck cancer patients

BACKGROUND: Area under time-concentration curve (AUC) of docetaxel is related with its toxicity and efficacy. The aim of this study is to investigate the target range of docetaxel AUC in Chinese head and neck cancer (HNC) patients. METHODS: Eligible HNC patients were enrolled and received at least 2...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Ma, Yuxiang, Lin, Qingguang, Yang, Yunpeng, Liang, Weiting, Salamone, S. J., Li, Yunying, Lin, Yuehao, Zhao, Hongyun, Zhao, Yuanyuan, Fang, Wenfeng, Huang, Yan, Zhang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154422/
https://ncbi.nlm.nih.gov/pubmed/32309383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.01.76
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