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The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study
BACKGROUND: The current study is aimed to examine the impact of pharmacokinetics and gene polymorphisms of enzymes involving in absorption, distribution, metabolism and excretion (ADME) on the efficacy of gefitinib in non-small cell lung cancer (NSCLC) patients. METHODS: Eligible patients with indic...
Gespeichert in:
Veröffentlicht in: | Ann Transl Med |
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Hauptverfasser: | , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
AME Publishing Company
2019
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989872/ https://ncbi.nlm.nih.gov/pubmed/32042822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.60 |
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