The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study

BACKGROUND: The current study is aimed to examine the impact of pharmacokinetics and gene polymorphisms of enzymes involving in absorption, distribution, metabolism and excretion (ADME) on the efficacy of gefitinib in non-small cell lung cancer (NSCLC) patients. METHODS: Eligible patients with indic...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Ma, Yuxiang, Xin, Shuang, Lin, Qingguang, Zhuang, Wei, Zhao, Yuanyuan, Zhu, Xia, Zhao, Hongyun, Huang, Min, Xun, Xu, Yang, Yunpeng, Fang, Wenfeng, Zhang, Li, Wang, Xueding
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989872/
https://ncbi.nlm.nih.gov/pubmed/32042822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.60
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