Development of Quantitative Methylation-Specific Droplet Digital PCR (ddMSP) for Assessment of Natural Tregs

Regulatory T cells (Tregs) suppress immune responses in vivo in an antigen-specific manner. Of clinical relevance, Tregs can be isolated and expanded in vitro while maintaining immunoregulatory function. Tregs are classified as CD4(+)CD25(high)CD127(low) FOXP3(+) cells. Demethylation of the Treg-spe...

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Dades bibliogràfiques
Publicat a:Front Genet
Autors principals: Husseiny, Mohamed I., Fahmy, Ahmed, Du, Weiting, Gu, Angel, Garcia, Pablo, Ferreri, Kevin, Kandeel, Fouad
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154152/
https://ncbi.nlm.nih.gov/pubmed/32318096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00300
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