Inhibition of Female and Male Human Detrusor Smooth Muscle Contraction by the Rac Inhibitors EHT1864 and NSC23766

INTRODUCTION: Lower urinary tract symptoms (LUTS) due to overactive bladder (OAB) are caused by spontaneous detrusor contractions. Medical treatment with muscarinic receptor antagonists or β(3)-adrenoceptor agonists aims to inhibit detrusor contractions, but overall results are unsatisfactory. Conse...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Li, Bingsheng, Yu, Qingfeng, Wang, Ruixiao, Gratzke, Christian, Wang, Xiaolong, Spek, Annabel, Herlemann, Annika, Tamalunas, Alexander, Strittmatter, Frank, Waidelich, Raphaela, Stief, Christian G., Hennenberg, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154109/
https://ncbi.nlm.nih.gov/pubmed/32317972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00409
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