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Inhibition of prostate smooth muscle contraction and prostate stromal cell growth by the inhibitors of Rac, NSC23766 and EHT1864

BACKGROUND AND PURPOSE: Medical therapy of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) targets smooth muscle contraction in the prostate, or prostate growth. However, current therapeutic options are insufficient. Here, we investigated the role of Rac in the c...

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Foilsithe in:Br J Pharmacol
Main Authors: Wang, Y, Kunit, T, Ciotkowska, A, Rutz, B, Schreiber, A, Strittmatter, F, Waidelich, R, Liu, C, Stief, C G, Gratzke, C, Hennenberg, M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439884/
https://ncbi.nlm.nih.gov/pubmed/25631101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13099
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