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Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca(2+)-Oxalate Lithogenesis

Impaired homeostasis of the carboxylic acids oxalate and citrate, dramatically increases the risk for the formation of Ca(2+)-oxalate kidney stones, which is the most common form of kidney stones in humans. Renal homeostasis of oxalate and citrate is controlled by complex mechanisms including epithe...

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Pubblicato in:Front Pharmacol
Autori principali: Shimshilashvili, Liana, Aharon, Sara, Moe, Orson W., Ohana, Ehud
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154107/
https://ncbi.nlm.nih.gov/pubmed/32317970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00405
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