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Loss of Myeloid BMPR1a Alters Differentiation and Reduces Mouse Prostate Cancer Growth

The Bone Morphogenetic Protein (BMP) pathway is a member of the TGFβ signaling family and has complex roles in cancer. BMP signaling is rarely mutated and can be frequently overexpressed in many human cancers. The dichotomous role of BMPs as both tumor promoters and suppressors appears to be largely...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ihle, Claire L., Straign, Desiree M., Provera, Meredith D., Novitskiy, Sergey V., Owens, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154049/
https://ncbi.nlm.nih.gov/pubmed/32318332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00357
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