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Contribution of Rare Variants of the SLC22A12 Gene to the Missing Heritability of Serum Urate Levels
Gout is a common arthritis caused by monosodium urate crystals. The heritability of serum urate levels is estimated to be 30–70%; however, common genetic variants account for only 7.9% of the variance in serum urate levels. This discrepancy is an example of “missing heritability.” The “missing herit...
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| Yayımlandı: | Genetics |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Genetics Society of America
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153932/ https://ncbi.nlm.nih.gov/pubmed/32005656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.303006 |
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