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High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches

Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year. Many snake venoms cause severe coagulopathy that makes victims vulnerable to suffering life-threating haemorrhage. The m...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Slagboom, Julien, Mladić, Marija, Xie, Chunfang, Kazandjian, Taline D., Vonk, Freek, Somsen, Govert W., Casewell, Nicholas R., Kool, Jeroen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153897/
https://ncbi.nlm.nih.gov/pubmed/32236099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007802
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