Overproduction of IL-2 by Cbl-b deficient CD4(+) T cells provides resistance against regulatory T cells

Regulatory T cells are integral to the regulation of autoimmune and anti-tumor immune responses. However, several studies have suggested that changes in T cell signaling networks can result in T cells that are resistant to the suppressive effects of regulatory T cells. Here, we investigated the role...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Han, SeongJun, Chung, Douglas C., St. Paul, Michael, Liu, Zhe Qi, Garcia-Batres, Carlos, Elford, Alisha R., Tran, Charles W., Chapatte, Laurence, Ohashi, Pamela S.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153846/
https://ncbi.nlm.nih.gov/pubmed/32313719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1737368
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