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Effect of lofexidine on cardiac repolarization during treatment of opioid withdrawal

BACKGROUND: Lofexidine is a non-opioid treatment for opioid withdrawal syndrome. Its sympatholytic actions counteract the noradrenergic hyperactivity that occurs during abrupt opioid withdrawal. METHODS: The effect of lofexidine 2.16 and 2.88 mg/day on QTcF (QT interval, heart-rate corrected, Frider...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Alcohol Depend
Egile Nagusiak: Darpö, Börje, Pirner, Mark, Longstreth, James, Ferber, Georg
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153804/
https://ncbi.nlm.nih.gov/pubmed/31606589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2019.107596
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