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Effect of lofexidine on cardiac repolarization during treatment of opioid withdrawal
BACKGROUND: Lofexidine is a non-opioid treatment for opioid withdrawal syndrome. Its sympatholytic actions counteract the noradrenergic hyperactivity that occurs during abrupt opioid withdrawal. METHODS: The effect of lofexidine 2.16 and 2.88 mg/day on QTcF (QT interval, heart-rate corrected, Frider...
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| Published in: | Drug Alcohol Depend |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153804/ https://ncbi.nlm.nih.gov/pubmed/31606589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2019.107596 |
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