Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease

Psoriasis is characterized by hyperproliferation and defective differentiation of keratinocytes (KCs). Patients with psoriasis are at a high risk of developing diabetes and cardiovascular diseases. The debate on the genetic origin of psoriasis pathogenesis remains unresolved due to lack of suitable...

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Vydáno v:Stem Cells Dev
Hlavní autoři: Ali, Gowher, Elsayed, Ahmed K., Nandakumar, Manjula, Bashir, Mohammed, Younis, Ihab, Abu Aqel, Yasmin, Memon, Bushra, Temanni, Ramzi, Abubaker, Fadhil, Taheri, Shahrad, Abdelalim, Essam M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2020
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153648/
https://ncbi.nlm.nih.gov/pubmed/31996098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2019.0150
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