Gene Expression and Epigenetic Changes in Mice Following Inhalation of Copper(II) Oxide Nanoparticles

We investigated the transcriptomic response and epigenetic changes in the lungs of mice exposed to inhalation of copper(II) oxide nanoparticles (CuO NPs) (8 × 10(5) NPs/m(3)) for periods of 3 days, 2 weeks, 6 weeks, and 3 months. A whole genome transcriptome and miRNA analysis was performed using ne...

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Veröffentlicht in:Nanomaterials (Basel)
Hauptverfasser: Rossner, Pavel, Vrbova, Kristyna, Rossnerova, Andrea, Zavodna, Tana, Milcova, Alena, Klema, Jiri, Vecera, Zbynek, Mikuska, Pavel, Coufalik, Pavel, Capka, Lukas, Krumal, Kamil, Docekal, Bohumil, Holan, Vladimir, Machala, Miroslav, Topinka, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153614/
https://ncbi.nlm.nih.gov/pubmed/32197515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10030550
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