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Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549)

We investigated the toxicity of benzo[a]pyrene (B[a]P), 1-nitropyrene (1-NP) and 3-nitrobenzanthrone (3-NBA) in A549 cells. Cells were treated for 4 h and 24 h with: B[a]P (0.1 and 1 μM), 1-NP (1 and 10 μM) and 3-NBA (0.5 and 5 μM). Bulky DNA adducts, lipid peroxidation, DNA and protein oxidation an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rossner, Pavel, Strapacova, Simona, Stolcpartova, Jitka, Schmuczerova, Jana, Milcova, Alena, Neca, Jiri, Vlkova, Veronika, Brzicova, Tana, Machala, Miroslav, Topinka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037673/
https://ncbi.nlm.nih.gov/pubmed/27571070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091393
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