Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development

Epigenetic modifications, including DNA methylation and histone modifications, are reprogrammed considerably following fertilization during mammalian early embryonic development. Incomplete epigenetic reprogramming is a major factor leading to poor developmental outcome in embryos generated by assis...

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Veröffentlicht in:Epigenetics
Hauptverfasser: Zhao, Panpan, Wang, Huanan, Wang, Han, Dang, Yanna, Luo, Lei, Li, Shuang, Shi, Yan, Wang, Lefeng, Wang, Shaohua, Mager, Jesse, Zhang, Kun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153544/
https://ncbi.nlm.nih.gov/pubmed/31533525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1669375
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