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Pharmacologic inhibition of RGD‐binding integrins ameliorates fibrosis and improves function following kidney injury
Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine–glycine–aspartic acid (RGD)‐binding integrins are important mediators of the pro‐fibrotic response by activating latent TGF‐β at sites of injury and by providing myofibroblasts information about...
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| Publicado no: | Physiol Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153038/ https://ncbi.nlm.nih.gov/pubmed/32281744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14329 |
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