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Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS

Naringenin (NAR), 4′,5,7-trihydroxydihydroflavone, has a wide range of pharmacological activities but shows poor water solubility and low bioavailability. The pharmacokinetics and bioavailability of naringenin-nicotinamide cocrystal (NAR-NCT), which offers improved solubility, were evaluated in this...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Xu, Dan, Zhang, Gui-Qiu, Zhang, Ting-Ting, Jin, Bo, Ma, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152953/
https://ncbi.nlm.nih.gov/pubmed/32322425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8364218
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