Superiority of Droplet Digital PCR Over Real-Time Quantitative PCR for JAK2 V617F Allele Mutational Burden Assessment in Myeloproliferative Neoplasms: A Retrospective Study

JAK2V617F mutational status is an essential diagnostic index in myeloproliferative neoplasms (MPNs). Although widely used for detection of JAK2 V617F mutation in peripheral blood (PB), sensitive real-time quantitative PCR (qPCR) presents some methodological limitations. Recently, emerging alternativ...

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Veröffentlicht in:Diagnostics (Basel)
Hauptverfasser: La Rocca, Francesco, Grieco, Vitina, Ruggieri, Vitalba, Zifarone, Emanuela, Villani, Oreste, Zoppoli, Pietro, Russi, Sabino, Laurino, Simona, Falco, Geppino, Calice, Giovanni, Marinaccio, Anna, Natalicchio, Maria Iole, Albano, Francesco, Musto, Pellegrino
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151190/
https://ncbi.nlm.nih.gov/pubmed/32150880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics10030143
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