A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

Alzheimer’s disease (AD) is the leading cause of dementia. Non-competitive N-Methyl-D-aspartate (NMDA) receptor antagonist memantine improved cognition and molecular alterations after preclinical treatment. Nevertheless, clinical results are discouraging. In vivo efficacy of the RL-208, a new NMDA r...

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Publicat a:Pharmaceutics
Autors principals: Companys-Alemany, Júlia, Turcu, Andreea L., Bellver-Sanchis, Aina, Loza, Maria I, Brea, José M., Canudas, Anna M, Leiva, Rosana, Vázquez, Santiago, Pallàs, Mercè, Griñán-Ferré, Christian
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151078/
https://ncbi.nlm.nih.gov/pubmed/32235699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030284
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