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Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This model can determine intestinal permeability ba...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Dahlgren, David, Cano-Cebrián, Maria-Jose, Olander, Tobias, Hedeland, Mikael, Sjöblom, Markus, Lennernäs, Hans
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150977/
https://ncbi.nlm.nih.gov/pubmed/32182653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030242
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