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SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Yang, Hua, Mo, Jiayin, Xiang, Qi, Zhao, Peiyi, Song, Yunting, Yang, Ge, Wu, Kailang, Liu, Yingle, Liu, Weiyong, Wu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150879/
https://ncbi.nlm.nih.gov/pubmed/32121397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030273
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