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SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of...

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Bibliografske podrobnosti
izdano v:Viruses
Main Authors: Yang, Hua, Mo, Jiayin, Xiang, Qi, Zhao, Peiyi, Song, Yunting, Yang, Ge, Wu, Kailang, Liu, Yingle, Liu, Weiyong, Wu, Jianguo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150879/
https://ncbi.nlm.nih.gov/pubmed/32121397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030273
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