Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...

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Publicat a:Pharmaceutics
Autors principals: Lazaridou, Maria, Christodoulou, Evi, Nerantzaki, Maria, Kostoglou, Margaritis, Lambropoulou, Dimitra A., Katsarou, Angeliki, Pantopoulos, Kostas, Bikiaris, Dimitrios N.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150847/
https://ncbi.nlm.nih.gov/pubmed/32156022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030238
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