Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)

The objective of this study was to develop chitosan (CS) nanoparticles (NPs) loaded with deferoxamine mesylate (DFO) for slow release of this iron-chelating drug. Drug nanoencapsulation was performed via ionic gelation of chitosan using sodium tripolyphosphate (TPP) as cross-linker. Nanoparticles wi...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Lazaridou, Maria, Christodoulou, Evi, Nerantzaki, Maria, Kostoglou, Margaritis, Lambropoulou, Dimitra A., Katsarou, Angeliki, Pantopoulos, Kostas, Bikiaris, Dimitrios N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150847/
https://ncbi.nlm.nih.gov/pubmed/32156022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030238
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