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Alzheimer’ss Disease Pathology in ApoE Transgenic Mouse Models: The Who, What, When, Where, Why, and How

The focus on amyloid plaques and neurofibrillary tangles has yielded no Alzheimer’s disease (AD) modifying treatments in the past several decades, despite successful studies in preclinical mouse models. This inconsistency has caused a renewed focus on improving the fidelity and reliability of AD mou...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Lewandowski, Cutler T., Weng, Juan Maldonado, LaDu, Mary Jo
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150653/
https://ncbi.nlm.nih.gov/pubmed/32087290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104811
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