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Alzheimer’ss Disease Pathology in ApoE Transgenic Mouse Models: The Who, What, When, Where, Why, and How

The focus on amyloid plaques and neurofibrillary tangles has yielded no Alzheimer’s disease (AD) modifying treatments in the past several decades, despite successful studies in preclinical mouse models. This inconsistency has caused a renewed focus on improving the fidelity and reliability of AD mou...

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Lewandowski, Cutler T., Weng, Juan Maldonado, LaDu, Mary Jo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150653/
https://ncbi.nlm.nih.gov/pubmed/32087290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104811
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