Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model

Traumatic brain injury (TBI) results in a decrease in glutamate transporter-1 (GLT-1) expression, the major mechanism for glutamate removal from synapses. Coupled with an increase in glutamate release from dead and dying neurons, this causes an increase in extracellular glutamate. The ensuing glutam...

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Bibliographic Details
Published in:Cereb Cortex
Main Authors: Hameed, Mustafa Q, Hsieh, Tsung-Hsun, Morales-Quezada, Leon, Lee, Henry H C, Damar, Ugur, MacMullin, Paul C, Hensch, Takao K, Rotenberg, Alexander
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150617/
https://ncbi.nlm.nih.gov/pubmed/30590449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy328
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