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Advances in CRISPR/Cas-based Gene Therapy in Human Genetic Diseases
CRISPR/Cas genome editing is a simple, cost effective, and highly specific technique for introducing genetic variations. In mammalian cells, CRISPR/Cas can facilitate non-homologous end joining, homology- directed repair, and single-base exchanges. Cas9/Cas12a nuclease, dCas9 transcriptional regulat...
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| Publié dans: | Theranostics |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ivyspring International Publisher
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7150498/ https://ncbi.nlm.nih.gov/pubmed/32292501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43360 |
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