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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome

Rationale: Epigenetic mechanisms are fundamental processes that can modulate gene expression, allowing cellular adaptation to environmental conditions. Hypoxia is an important factor known to initiate the metastatic cascade in cancer, activating cell motility and invasion by silencing cell adhesion...

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Publicat a:Theranostics
Autors principals: Casciello, Francesco, Al-Ejeh, Fares, Miranda, Mariska, Kelly, Greg, Baxter, Eva, Windloch, Karolina, Gannon, Frank, Lee, Jason S
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150496/
https://ncbi.nlm.nih.gov/pubmed/32292512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41453
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