A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques

Human infection by Zika virus (ZIKV) during pregnancy can lead to vertical transmission and fetal aberrations, including microcephaly. Prophylactic administration of antibodies can diminish or prevent ZIKV infection in animal models, but whether passive immunization can protect nonhuman primates and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Van Rompay, Koen K. A., Coffey, Lark L., Kapoor, Tania, Gazumyan, Anna, Keesler, Rebekah I., Jurado, Andrea, Peace, Avery, Agudelo, Marianna, Watanabe, Jennifer, Usachenko, Jodie, Singapuri, Anil, Immareddy, Ramya, Ardeshir, Amir, Stuart, Jackson B., Bournazos, Stylianos, Ravetch, Jeffrey V., Balderes, Paul J., Lorenz, Ivo C., Esswein, Shannon R., Keeffe, Jennifer R., Bjorkman, Pamela J., Wang, Qiao, Rice, Charles M., MacDonald, Margaret R., Nussenzweig, Michel C., Robbiani, Davide F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7149495/
https://ncbi.nlm.nih.gov/pubmed/32209664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000414117
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