Coordination of mRNA and tRNA methylations by TRMT10A

The posttranscriptional modification of messenger RNA (mRNA) and transfer RNA (tRNA) provides an additional layer of regulatory complexity during gene expression. Here, we show that a tRNA methyltransferase, TRMT10A, interacts with an mRNA demethylase FTO (ALKBH9), both in vitro and inside cells. TR...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Ontiveros, R. Jordan, Shen, Hui, Stoute, Julian, Yanas, Amber, Cui, Yixiao, Zhang, Yuyu, Liu, Kathy Fange
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7149399/
https://ncbi.nlm.nih.gov/pubmed/32213595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913448117
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