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Testosterone increases apoptotic cell death and decreases mitophagy in Leber’s hereditary optic neuropathy cells

Leber’s hereditary optic neuropathy (LHON) is one of the most common mitochondrial diseases caused by point mutations in mitochondrial DNA (mtDNA). The majority of diagnosed LHON cases are caused by a point mutation at position 11,778 in the mitochondrial genome. LHON mainly affects young men in the...

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Détails bibliographiques
Publié dans:J Appl Genet
Auteurs principaux: Jankauskaitė, Elona, Ambroziak, Anna Maria, Hajieva, Parvana, Ołdak, Monika, Tońska, Katarzyna, Korwin, Magdalena, Bartnik, Ewa, Kodroń, Agata
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148285/
https://ncbi.nlm.nih.gov/pubmed/32157656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-020-00550-y
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