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Testosterone increases apoptotic cell death and decreases mitophagy in Leber’s hereditary optic neuropathy cells
Leber’s hereditary optic neuropathy (LHON) is one of the most common mitochondrial diseases caused by point mutations in mitochondrial DNA (mtDNA). The majority of diagnosed LHON cases are caused by a point mutation at position 11,778 in the mitochondrial genome. LHON mainly affects young men in the...
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| Publié dans: | J Appl Genet |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7148285/ https://ncbi.nlm.nih.gov/pubmed/32157656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-020-00550-y |
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