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Testosterone increases apoptotic cell death and decreases mitophagy in Leber’s hereditary optic neuropathy cells

Leber’s hereditary optic neuropathy (LHON) is one of the most common mitochondrial diseases caused by point mutations in mitochondrial DNA (mtDNA). The majority of diagnosed LHON cases are caused by a point mutation at position 11,778 in the mitochondrial genome. LHON mainly affects young men in the...

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Detaylı Bibliyografya
Yayımlandı:J Appl Genet
Asıl Yazarlar: Jankauskaitė, Elona, Ambroziak, Anna Maria, Hajieva, Parvana, Ołdak, Monika, Tońska, Katarzyna, Korwin, Magdalena, Bartnik, Ewa, Kodroń, Agata
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148285/
https://ncbi.nlm.nih.gov/pubmed/32157656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-020-00550-y
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