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Cell type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation

New protein synthesis is known to be required for the consolidation of memories, yet existing methods to block translation lack spatiotemporal precision and cell-type specificity, preventing investigation of cell-specific contributions of protein synthesis. Here, we developed a combined knock-in mou...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Shrestha, Prerana, Ayata, Pinar, Herrero-Vidal, Pedro, Longo, Francesco, Gastone, Alexandra, Ledoux, Joseph E., Heintz, Nathaniel, Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147976/
https://ncbi.nlm.nih.gov/pubmed/31959934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0568-z
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