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No Evidence for Widespread Positive Selection Signatures in Common Risk Alleles Associated with Schizophrenia

Schizophrenia poses an evolutionary-genetic paradox as it exhibits strongly negative fitness effects (early mortality and decreased fecundity), yet it persists at a prevalence of approximately 1% worldwide. Evidence from several studies have suggested that schizophrenia is evolved and maintained in...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Yao, Yao, Yang, Jia, Xie, Yimin, Liao, Hai, Yang, Baoying, Xu, Qi, Rao, Shuquan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147583/
https://ncbi.nlm.nih.gov/pubmed/31150552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz048
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