Liposomal Delivery Improves the Efficacy of Prednisolone to Attenuate Renal Inflammation in a Mouse Model of Acute Renal Allograft Rejection

BACKGROUND. Systemic exposure to high-dose corticosteroids effectively combats acute rejection after kidney transplantation, but at the cost of substantial side effects. In this study, a murine acute renal allograft rejection model was used to investigate whether liposomal-encapsulated prednisolone...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: van Alem, Carla M.A., Schmidbauer, Martina, Rong, Song, Derlin, Katja, Schmitz, Jessica, Bräsen, Jan H., Thorenz, Anja, Chen, Rongjun, Ruben, Jurjen M., Winter, Elizabeth M., Schilperoort, Maaike, Kooijman, Sander, Lalai, Reshma A., Metselaar, Josbert M., Klemann, Christian, Meier, Martin, van Kooten, Cees, Gueler, Faikah, Rotmans, Joris I.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Original Basic Science—General
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147400/
https://ncbi.nlm.nih.gov/pubmed/31929419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000003060
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