Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury

Background: Ischemia reperfusion injury (IRI) plays a major role in solid organ transplantation. The length of warm ischemia time is critical for the extent of tissue damage in renal IRI. In this experimental study we hypothesized that local release of labile heme in renal tissue is triggered by the...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wang, Li, Vijayan, Vijith, Jang, Mi-Sun, Thorenz, Anja, Greite, Robert, Rong, Song, Chen, Rongjun, Shushakova, Nelli, Tudorache, Igor, Derlin, Katja, Pradhan, Pooja, Madyaningrana, Kukuh, Madrahimov, Nodir, Bräsen, Jan Hinrich, Lichtinghagen, Ralf, van Kooten, Cees, Huber-Lang, Markus, Haller, Hermann, Immenschuh, Stephan, Gueler, Faikah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933315/
https://ncbi.nlm.nih.gov/pubmed/31921212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02975
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