Brain iron deposition is linked with cognitive severity in Parkinson’s disease

BACKGROUND: Dementia is common in Parkinson’s disease (PD) but measures that track cognitive change in PD are lacking. Brain tissue iron accumulates with age and co-localises with pathological proteins linked to PD dementia such as amyloid. We used quantitative susceptibility mapping (QSM) to detect...

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Bibliographic Details
Published in:J Neurol Neurosurg Psychiatry
Main Authors: Thomas, George Edward Calver, Leyland, Louise Ann, Schrag, Anette-Eleonore, Lees, Andrew John, Acosta-Cabronero, Julio, Weil, Rimona Sharon
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
Subjects:
Movement Disorders
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147185/
https://ncbi.nlm.nih.gov/pubmed/32079673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2019-322042
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