Mechanisms of FH Protection Against Neovascular AMD

A common allele (402H) of the complement factor H (FH) gene is the major risk factor for age-related macular degeneration (AMD), the leading cause of blindness in the elderly population. Development and progression of AMD involves vascular and inflammatory components partly by deregulation of the al...

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Udgivet i:Front Immunol
Main Authors: Borras, Céline, Delaunay, Kimberley, Slaoui, Yousri, Abache, Toufik, Jorieux, Sylvie, Naud, Marie-Christine, Sanharawi, Mohamed El, Gelize, Emmanuelle, Lassiaz, Patricia, An, Na, Kowalczuk, Laura, Ayassami, Cédric, Moulin, Alexandre, Behar-Cohen, Francine, Mascarelli, Frédéric, Dinet, Virginie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146894/
https://ncbi.nlm.nih.gov/pubmed/32318056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00443
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